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Scientists have discovered a genetic form of Alzheimer’s disease, occurring in those who inherit two copies of the APOE4 gene, for the first time. The APOE4 gene, known to increase the risk of Alzheimer’s, can cause symptoms to appear seven to ten years earlier in those with two copies of the gene compared to others with different risk factors, according to a study from the Sant Pau Research Institute. This revelation marks a significant break from traditional views, implying a genetic cause for some Alzheimer’s cases. Approximately 15% of Alzheimer’s patients carry two APOE4 genes, highlighting the need to develop treatments targeting this gene. However, the findings do not suggest that individuals should rush for genetic testing since this gene duo is not responsible for most cases of Alzheimer’s.
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Research indicates that certain Alzheimer’s cases may be linked to duplicates of a specific gene.
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